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Apremilast impurity 12

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Apremilast impurity 12, >98%

CAS No. : [1384440-16-7]

Synonyms : N-Desacetyl O4-desmethyl apremilast

IUPAC Name : (S)-4-Amino-2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione

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Chemical Properites
Mol. Formula :
C19H20N2O6S
Mol. Weight :
404.44
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Apremilast, which is a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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