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Apremilast impurity 13

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SL-2495

Apremilast impurity 13, >98%

CAS No. : [1384439-79-5]

MDL No. : MFCD28386774

Synonyms : O4-Desmethyl O3-desethyl apremilast

IUPAC Name : (S)-N-(2-(1-(3,4-Dihydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

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Chemical Properites
Mol. Formula :
C19H18N2O7S
Mol. Weight :
418.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Apremilast, which is a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L. G. et al.: J. Chromatogr Sci. 54(8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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