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Apremilast impurity 5

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SL-2485

Apremilast impurity 5, 98%

CAS No. : [2095036-40-9]

IUPAC Name : (S)-2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-4-nitroisoindoline-1,3-dione

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We accept
Chemical Properites
Mol. Formula :
C20H20N2O8S
Mol. Weight :
448.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a key starting material and an impurity during the preparation of Apremilast. A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L. G. et al.: J. Chromatogr Sci. 54(8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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