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Aprepitant-d3

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Aprepitant-d3, >98% (CP)

Isotopic Purity : 99 atom % D

Related CAS No. : [170729-80-3] of the unlabelled compound

Synonyms : Emend-d3; L 754030-d3; MK 0869-d3; MK 869-d3; ONO 7436-d3

IUPAC Name : 5-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy-2,2,2-d3)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H18D3F7N4O3
Mol. Weight :
537.45
Appearance :
Beige solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Aprepitant-d3 is a deuterium labelled version an analog of Aprepitant, which is a specific NK-1R antagonist, used as an antiemetic agent.

References : Martinez A. N.: et al.: J. Neuroinflammation 14(1), 37, 2017; Bayati S. et al.: Eur J. Pharmacol. 791, 274-283, 2016; Mannangatti P. et al.: Psychopharmacology (Berl). 234(4), 695-705, 2017; Barrett J. S. et al.: J.Transl Med.,14(1), 148, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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