Aprepitant-d4

SL-2036

Aprepitant-d₄, >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [1133387-60-6]

Related CAS No. : [170729-80-3] of the unlabelled compound

Synonyms : Emend-d₄; L 754030-d₄; MK 0869-d₄; MK 869-d₄; ONO 7436-d₄

IUPAC Name : 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d₄)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Aprepitant-d₄ is a deuterium labelled version an analog of Aprepitant, which is a specific NK-1R antagonist, used as an antiemetic agent.

References : Martinez A. N.: et al.: J. Neuroinflammation. 14(1), 37, 2017; Bayati S. et al.: Eur J. Pharmacol. 791, 274-283,2016; Mannangatti P. et al.: Psychopharmacology (Berl). 234(4), 695-705, 2017; Barrett J. S. et al.: J.Transl Med.,14(1), 148, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.