Aprepitant M2 metabolite (1S, 2S, 3R)-isomer

SL-7194

Aprepitant M2 metabolite (1S, 2S, 3R)-isomer, >98%

CAS No. : [327623-37-0]

Synonyms : Aprepitant M2 metabolite enantiomer

IUPAC Name : (2S,3R)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine

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10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : This is a metabolite of Aprepitant (Aprepitant M2 metabolite (1S, 2S, 3R)-isomer), which is a specific NK-1R antagonist. It is used as an antiemetic agent.

References : Martinez A. N.: et al.: J. Neuroinflammation 14(1), 37, 2017; Bayati S. et al.: Eur J. Pharmacol., 791, 274-283, 2016; Mannangatti P. et al.: Psychopharmacology (Berl.) 234(4), 695-705, 2017; Barrett J. S. et al.: J. Transl Med.,14(1), 148, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.