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Aripiprazole N1-oxide

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SL-1368

Aripiprazole N1-oxide, >98%

CAS No. : [573691-09-5]

MDL No. : MFCD19704885

Synonyms : Aripiprazole EP impurity F

IUPAC Name : 7-[4-[4-(2,3-Dichlorophenyl)-1-oxido-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone

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Chemical Properites
Mol. Formula :
C23H27Cl2N3O3
Mol. Weight :
464.38
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Aripiprazole N1-oxide is a metabolite and an impurity of Aripiprazole, which is a human 5-HT1A receptor partial agonist and anti-psychotic drug.

References : Rowley M. et al.: J. Med. Chem., 44, 477, 2001; McGavin J. et al.: CNS Drugs, 16, 779, 2002; Ozdemir V. et al.: Curr. Opin. Invest Drugs 3, 113, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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