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Asciminib

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SI-1045

Asciminib, >98% (HPLC)

CAS No. : [1492952-76-7]

MDL No. : MFCD31560488

Synonyms : ABL-001

IUPAC Name : (S)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-5-yl)nicotinamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG95.00
In Stock  Estimated to ship on 20 September 2026
10MG155.00
In Stock  Estimated to ship on 20 September 2026
25MG255.00
In Stock  Estimated to ship on 20 September 2026
50MG455.00
In Stock  Estimated to ship on 20 September 2026
100MG855.00
In Stock  Estimated to ship on 20 September 2026
250MG1655.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C20H18ClF2N5O3
Mol. Weight :
449.84
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Asciminib is a potent and selective allosteric ABL1 inhibitor with IC50 of 0.25 nM in BCR–ABL1-transformed BaF3 cells.. It is used to treat a certain type of chronic myeloid leukemia (CML).

References : Schoepfer J. et al.: J. Med. Chem., 61(18), 8120-8135, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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