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Asciminib-d4

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Asciminib-d4, >98%

Related CAS No. : [1492952-76-7] of the unlabelled compound

IUPAC Name : (S)-N-(4-(Chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl-2,2,5,5-d4)-5-(1H-pyrazol-5-yl)nicotinamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C20H14D4ClF2N5O3
Mol. Weight :
453.87
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium-labelled version of Asciminib, which is a potent and selective allosteric ABL1 inhibitor. Asciminib is used to treat a certain type of chronic myeloid leukemia (CML).

References : Schoepfer J. et al.: J. Med. Chem., 61(18), 8120-8135, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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