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Asenapine maleate

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SI-2698

Asenapine maleate, >98% (HPLC)

CAS No. : [85650-56-2]

MDL No. : MFCD00900588

Synonyms : Org 5222 maleate

IUPAC Name : (3aS,12bS)-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H-dibenzo[2,3:6,7]oxepino[4,5-c]pyrrole maleate

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Chemical Properites
Mol. Formula :
C17H16ClNO . C4H4O4
Mol. Weight :
401.84
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Asenapine maleate is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 antagonist with Ki values of 0.03-4.0 nM, 1.3nM, respectively, and an antipsychotic.

References : Stoner S. C. et al.: Clin Ther., 34(5), 1023-1040, 2012; Shahid M. et al.: J. Psychopharmacol., 23(1), 65-73, 2009; Ohyama M. et al.: Acta Neuropsychiatr., 28(6), 327-336, 2016; Ene H. M. et al.: Acta Neuropsychiatr., 28(2), 85-91, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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