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ASP-5878

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SI-8130

ASP-5878, >98% (HPLC)

CAS No. : [1453208-66-6]

IUPAC Name : 2-(4-((5-((2,6-Difluoro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)ethan-1-ol

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C18H19F2N5O4
Mol. Weight :
407.38
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ASP-5878 is an oral FGFR inhibitor with strong activity across FGFR1–4 (IC50 = 0.47/0.6/0.74/3.5 nM). It demonstrates antitumor potential and is suitable for probing FGFR‑dependent signaling pathways and cancer models.

References : Futami T. et al.: Mol. Cancer Ther., 16(1), 68-75, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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