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Aspirin-acyl-d3-beta-D-glucuronide

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SL-978

Aspirin-acyl-d3-β-D-glucuronide, >98% (CP)

Isotopic Purity : 98 atom % D

Related CAS No. : [24719-72-0] of the unlabelled compound

Synonyms : Acetyl-d3 salicylic acid acyl-β-D-glucuronide

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Chemical Properites
Mol. Formula :
C15H13D3O10
Mol. Weight :
359.30
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications :

It is a deuterium labelled glucuronide metabolite of Aspirin-d3. Aspirin is a non-selective, irreversible COX inhibitor. Aspirin acetylates COX-1 at Ser530 and COX-2 at Ser516 resulting in irreversible enzyme inhibition. This can be used as an internal reference standard.

References : Johnson J. L. et al.: Arch. Biochem. Biophys. 324, 26-34,1995.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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