AT-13148

SI-6812

AT-13148, >98% (HPLC)

CAS No. : [1056901-62-2]

IUPAC Name : (S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethan-1-ol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : AT-13148 is an orally active, ATP‑competitive inhibitor with broad activity across AGC kinases, including Akt1/2/3 (IC₅₀ = 38/402/50 nM), p70S6K (8 nM), PKA (3 nM), and ROCKI/II (6/4 nM). Its multi‑target profile makes it a valuable tool for dissecting AGC‑regulated pathways and evaluating therapeutic strategies in oncology.

References : Yap T. A. et al.: Clin. Cancer Res., 18(14), 3912-23, 2012; Xi. Y. et al.: Biochem Biophys. Res. Commun., 478(1), 330-6, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.