AT-7519

SI-7781

AT-7519, >98% (HPLC)

CAS No. : [844442-38-2]

Synonyms : AT-7519M

IUPAC Name : 4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : AT-7519 inhibits multiple CDKs with IC₅₀ values ranging from <10 nM to 210 nM, including CDK1, CDK2, CDK4–6, CDK5, and CDK9. This broad inhibitory spectrum makes it a versatile tool compound for probing CDK‑dependent pathways in proliferation and transcription.

References : Wyatt P. G. et al.: J. Med. Chem., 51(16), 4986-99, 2008; Squires M. S. et al.: Mol. Cancer Ther., 8(2), 324-32, 2009; Dolman M. E. et al.: Clin. Cancer Res., 21(22), 5100-9, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.