Atabecestat

SI-6157

Atabecestat, >98% (HPLC)

CAS No. : [1200493-78-2]

Synonyms : JNJ-54861911

IUPAC Name : (S)-N-(3-(2-Amino-4-methyl-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Atabecestat is a potent BACE1 inhibitor with excellent oral activity and CNS penetration, producing high and sustained reductions in CSF Aβ. It shows good tolerability and long‑lasting PK/PD behavior, making it a valuable tool for investigating amyloid‑lowering strategies in Alzheimer’s disease.

References : Timmers M. et al.: Alzheimers Dement (N Y), 2(3), 202-212, 2016; Janssens J. et al. : Neurobiol. Dis., 154, 105365, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.