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Atopaxar hydrobromide

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SI-5420

Atopaxar hydrobromide, >98% (HPLC)

CAS No. : [474550-69-1]

MDL No. : MFCD25371545

Synonyms : E5555 hydrobromide; ER-172594-00 hydrobromide

IUPAC Name : 1-(3-(tert-Butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoisoindolin-2-yl)ethan-1-one hydrobromide

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Chemical Properites
Mol. Formula :
C29H38FN3O5 . HBr
Mol. Weight :
608.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Atopaxar hydrobromide is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor 1 (PAR1) antagonist. Atopaxar hydrobromide, an antiplatelet agent, interferes with platelet signaling. Atopaxar hydrobromide can be used for the research of atherothrombotic disease.

References : Dockendorff C. et al.: ACS Med Chem Lett., 3(3), 232–237, 2012; Kogushi M. et al.: Eur. J. Pharmacol., 657(1-3), 131-137, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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