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Atuveciclib

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SI-6835

Atuveciclib, >98% (HPLC)

CAS No. : [2923012-24-0]

Synonyms : BAY-1143572

IUPAC Name : (R)-(3-((4-(4-Fluoro-2-methoxyphenyl)-1,3,5-triazin-2-yl)amino)benzyl)(imino)(methyl)-l6-sulfanone

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Chemical Properites
Mol. Formula :
C18H18FN5O2S
Mol. Weight :
387.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Atuveciclib selectively targets P‑TEFb/CDK9 with nanomolar potency (IC50 = 13 nM) and is orally active. Its strong CDK9‑inhibitory profile supports its use in research on transcriptional control and CDK9‑driven malignancies.

References : Lücking U. et al.:Chem. Med. Chem., 12(21), 1776-1793, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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