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Atuveciclib

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SI-7423

Atuveciclib, >98% (HPLC)

CAS No. : [1414943-94-4]

Synonyms : BAY-1143572

IUPAC Name : (3-((4-(4-Fluoro-2-methoxyphenyl)-1,3,5-triazin-2-yl)amino)benzyl)(imino)(methyl)-l6-sulfanone

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Chemical Properites
Mol. Formula :
C18H18FN5O2S
Mol. Weight :
387.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Atuveciclib is an orally active and selective P‑TEFb/CDK9 inhibitor that blocks CDK9/cyclin T1 with an IC50 of 13 nM. Its activity profile supports its use in studies of CDK9‑regulated transcription and oncogenic signaling.

References : Lucking U. et al.: ChemMedChem., 12(21), 1776-1793, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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