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Atuveciclib (S)-enantiomer

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SI-6837

Atuveciclib (S)-enantiomer, >98% (HPLC)

CAS No. : [2250279-81-1]

Synonyms : (+)-Atuveciclib; BAY-1143572 (S)-enantiomer; (+)-BAY-1143572

IUPAC Name : (S)-(3-((4-(4-Fluoro-2-methoxyphenyl)-1,3,5-triazin-2-yl)amino)benzyl)(imino)(methyl)-l6-sulfanone

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Chemical Properites
Mol. Formula :
C18H18FN5O2S
Mol. Weight :
387.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Atuveciclib (S)‑enantiomer selectively targets CDK9 with nanomolar potency (IC50 = 16 nM) and represents the stereochemically resolved form of Atuveciclib. It is useful for studying CDK9‑mediated transcriptional control and related disease biology.

References : Lücking U et al.:Chem. Med. Chem., 12(21), 1776-1793, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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