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Related CAS No. : [1374248-81-3] of the free base compound
Synonyms : CCX168 hydrochloride
IUPAC Name : (2R,3S)-2-(4-(Cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)-N-(4-methyl-3-(trifluoromethyl)phenyl)piperidine-3-carboxamide hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C33H35F4N3O2 • HCl | Mol. Weight : 618.11 |
Appearance : Off-white solid | Melting Point : Not available |
Solubility : MeOH | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Avacopan hydrochloride is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor with an IC50 of 0.1 nM. Avacopan is used to treat severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis.
References : Bekker P. et al.: PLoS One 11(10), e0164646, 2016; Xiao H. et al.: J. Am. Soc. Nephrol., 25(2), 225-31, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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