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Avacopan metabolite M1

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Avacopan metabolite M1, >98%

IUPAC Name : 2-(4-(Cyclopentylamino)phenyl)-1-(2-fluoro-6-methylbenzoyl)-N-(4-(hydroxymethyl)-3-(trifluoromethyl)phenyl)piperidine-3-carboxamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C33H35F4N3O3
Mol. Weight :
597.65
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Avacopan, which is a potent, selective and orally available complement 5a receptor (C5aR) inhibitor. Avacopan is used to treat severe active anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis.

References : Bekker P. et al.: PLoS One 11(10), e0164646, 2016; Xiao H. et al.: J. Am. Soc. Nephrol., 25(2), 225-31, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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