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Avatrombopag-d8 hydrochloride

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Avatrombopag-d8 hydrochloride, >98%

Synonyms : AKR-501-d8 hydrochloride; E5501-d8 hydrochloride; YM477-d8 hydrochloride

IUPAC Name : 1-(3-Chloro-5-((4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl-d8)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid hydrochloride

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C29H26D8Cl2N6O3S2 . HCl
Mol. Weight :
694.16
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Avatrombopag hydrochloride, which is an orally administered, small-molecule thrombopoietin receptor (c-Mpl) agonist which increases platelet number, but not platelet activation. Avatrombopag may help treat low blood platelet count in adults with immune thrombocytopenia (ITP) and chronic liver disease (CLD).

References : Fukushima-Shintani M. et al.: Eur. J. Haematol., 82(4), 247-254, 2009; Xu H. et al.: Expert Rev Clin Pharmacol., 12(9), 859-865, 2019; Nomoto M. et al.: Br. J. Clin Pharmacol., 84(5), 952-960, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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