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AVE 0991

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SI-5824

AVE 0991, >98% (HPLC)

CAS No. : [304462-19-9]

MDL No. : MFCD27992063

IUPAC Name : N-(Ethylcarbamoyl)-3-(4-((5-formyl-4-methoxy-2-phenyl-1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophene-2-sulfonamide

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Chemical Properites
Mol. Formula :
C29H32N4O5S2
Mol. Weight :
580.72
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AVE 0991 is a non-peptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM.

References : Wiemer G. et al.: Hypertension 40(6), 847-52, 2002; Pinheiro S. V. et al.: Hypertension 44(4), 490-6, 2004; Ferreira A. J. et al.: Am. J. Physiol Heart Circ Physiol., 292(2), H1113-9, 2007; Mo J. et al.: Redox Biol., 20, 75-86, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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