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Avotaciclib trihydrochloride

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SI-7788

Avotaciclib trihydrochloride, >98% (HPLC)

CAS No. : [1983984-01-5]

Synonyms : BEY-1107 trihydrochloride

IUPAC Name : 2,6-Bis(2-aminopyrimidin-4-yl)pyridin-3-ol trihydrochloride

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Chemical Properites
Mol. Formula :
C13H11N7O • 3HCl
Mol. Weight :
390.65
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Avotaciclib trihydrochloride selectively targets CDK1 and exhibits oral activity, leading to inhibition of tumor‑cell growth and induction of apoptosis. It has been utilized in research models of several cancer types, including pancreatic and lung cancers.

References : Seufferlein T. et al.: Translational Pancreatic Cancer Research, 219-232, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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