AZ-6197

SI-1178

AZ-6197, >98% (HPLC)

CAS No. : [2023003-94-1]

Synonyms : AZ6197

IUPAC Name : (R)-3-Methyl-7-(5-methyl-2-(1-methyl-1H-pyrazol-5-yl)pyrimidin-4-yl)-2-((6-methylpyridin-2-yl)methyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
10MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
25MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
50MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
100MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
250MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
Note: AZ-6197 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : AZ-6197 is a potent, selective, reversible inhibitor of ERK1/2 with IC₅₀ of <0.3 nM (ERK2), inhibits pERK/pRSK with IC₅₀ of 12/62 nM in A375 cells, respectively.

References : Richard A. W. et al.: J. Med. Chem., 60(8), 3438-3450, 2017; Didier D. et al.: Oncotarget., 9(31), 21674-21686, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.