AZ-628

SI-6511

AZ-628, >98% (HPLC)

CAS No. : [878739-06-1]

IUPAC Name : 3-(2-Cyanopropan-2-yl)-N-(4-methyl-3-((3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)phenyl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : AZ-628 inhibits B‑Raf (IC₅₀ = 105 nM), B‑Raf^V600E (IC₅₀ = 34 nM), and c‑Raf‑1 (IC₅₀= 29 nM), demonstrating pan‑Raf activity relevant to probing MAPK signaling and oncogenic Raf‑driven pathways.

References : Khazak V. et al.: Expert Opin Ther Targets, 11(12), 1587-609, 2007; Lau K. S. et al.: PLoS One, 7(7), e41343, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.