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AZD-4573

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SI-6834

AZD-4573, >98% (HPLC)

CAS No. : [2057509-72-3]

IUPAC Name : (1S,3R)-3-Acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexane-1-carboxamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H28ClN5O2
Mol. Weight :
429.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AZD-4573 selectively inhibits CDK9 with sub‑nanomolar potency (IC50< 4 nM) and is optimized for transient target engagement. By disrupting CDK9‑mediated transcriptional regulation, it demonstrates strong therapeutic potential in hematologic cancers.

References : Bernard Barlaam et al.: Cancer Research., 78(13), 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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