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AZD-5438

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SI-6390

AZD-5438, >98% (HPLC)

CAS No. : [602306-29-6]

IUPAC Name : 4-(1-Isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C18H21N5O2S
Mol. Weight :
371.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AZD‑5438 inhibits CDK1, CDK2, and CDK9 with low‑nanomolar potency and displays minimal activity against GSK3β, CDK5, and CDK6. This selectivity profile makes it a useful tool compound for dissecting CDK‑regulated cell‑cycle progression and transcriptional control.

References : Byth K. F. et al.: Mol. Cancer Ther., 8(7), 1856-66, 2009; Raghavan P. et al.: Int. J. Radiat Oncol. Biol. Phys., 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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