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AZD-6642

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SI-3665

AZD-6642, >98% (HPLC)

CAS No. : [1643809-54-4]

MDL No. : MFCD28902242

Synonyms : AZD6642

IUPAC Name : (S)-5-(4-(2-(4-(5-Aminopyrazin-2-yl)phenyl)tetrahydrofuran-2-yl)phenyl)-N-(2-hydroxy-2-methylpropyl)picolinamide

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Chemical Properites
Mol. Formula :
C30H31N5O3
Mol. Weight :
509.60
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AZD-6642 is a potential and selective 5-lipoxygenase activating protein (FLAP) inhibitor. AZD6642 shows high specific potency and low lipophilicity resulting in a selective and metabolically stable profile. Based on initial PK/PD relations a low dose to human was predicted.

References : Lemurell M. et al.: J. Med. Chem., 58(2), 897-911, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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