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AZD-7648

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SI-5964

AZD-7648, >98% (HPLC)

CAS No. : [2230820-11-6]

IUPAC Name : 7-Methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one

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Chemical Properites
Mol. Formula :
C18H20N8O2
Mol. Weight :
380.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AZD-7648 is a potent and selective inhibitor of DNA-PK with pharmacodynamic and monotherapy anti-tumor activity.

References : Fok L. H. J. et al.: Nature Commun.,10(1), 5065, 2019; Cadogan B. E. et al.: Cancer Res., 79 (13_Supplement): 3505, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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