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CAS No. : [1009298-09-2]
IUPAC Name : (5-(2,4-Bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C25H31N5O4 | Mol. Weight : 465.55 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : AZD‑8055 potently inhibits mTOR kinase activity (IC50= 0.8 nM) in an ATP‑competitive manner and blocks signaling through both mTORC1 and mTORC2. Its oral bioavailability supports its use in mechanistic and pharmacological studies of mTOR pathway regulation.
References : Chresta C. M. et al.: Cancer Res., 70(1), 288-98, 2010; Sini P. et al.: Autophagy, 6(4), 553-4, 2010; Jiang Q. et al.: Cancer Res., 71(12), 4074-84, 2011; Willems L. et al.: Leukemia, 26(6), 1195-202, 2012.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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