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AZD-9898

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SI-5481

AZD-9898, >98% (HPLC)

CAS No. : [2042347-69-1]

IUPAC Name : (1S,2S)-2-(5-((5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino)-3-methoxypyrazine-2-carbonyl)cyclopropane-1-carboxylic acid

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
We accept
Note: AZD-9898 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C20H19ClF3N3O4
Mol. Weight :
457.83
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : AZD-9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD-9898 mitigates the GABA binding and hepatic toxicity signal. AZD-9898 is developed for the new treatment of asthma.

References : Munck af Rosenschold M. et al.: J. Med. Chem., 62(17), 7769-7787, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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