Azenosertib

SI-6764

Azenosertib, >98% (HPLC)

CAS No. : [2376146-48-2]

Synonyms : ZN-c3

IUPAC Name : (R)-2-Allyl-1-(7-ethyl-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Azenosertib selectively inhibits WEE1 with nanomolar potency (IC₅₀ = 3.9 nM), disrupting G₂/M checkpoint signaling and enhancing sensitivity to DNA‑damaging stress. These properties underlie its pronounced antitumor activity.

References : Huang P. Q. et al.: J. Med. Chem., 10, 1021/acs.jmedchem.1c01121, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.