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SI-5314

Balicatib, >98% (HPLC)

CAS No. : [354813-19-7]

MDL No. : MFCD19443790

Synonyms : AAE581

IUPAC Name : N-(1-((Cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-yl)benzamide

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Chemical Properites
Mol. Formula :
C23H33N5O2
Mol. Weight :
411.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Balicatib is a potent and selective inhibitor of cathepsin K; 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.

References : Falgueyret J. P. et al.: J. Med Chem., 48(24), 7535-43, 2005; Vasiljeva O. et al.: Curr Pharm Des., 13(4), 387-403, 2007; Jerome C. et al.: Osteoporos Int., 22(12), 3001-11, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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