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Balovaptan

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SI-5701

Balovaptan, >98% (HPLC)

CAS No. : [1228088-30-9]

Synonyms : RG7314, RO5285119

IUPAC Name : 8-Chloro-5-methyl-1-((1r,4R)-4-(pyridin-2-yloxy)cyclohexyl)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine

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Chemical Properites
Mol. Formula :
C22H24ClN5O
Mol. Weight :
409.92
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Balovaptan is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism.

References : Ratni H. et al.: J. Med. Chem., 58(5), 2275-89, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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