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Baricitinib SEM impurity

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Baricitinib SEM impurity, >98%

CAS No. : [1187594-13-3]

IUPAC Name : 2-(1-(Ethylsulfonyl)-3-(4-(7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile

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25MGRequest A Quote
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Chemical Properites
Mol. Formula :
C22H31N7O3SSi
Mol. Weight :
501.68
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Baricitinib, which is a selective and orally bioavailable JAK1 and JAK2 inhibitor. Baricitinib is used for the treatment of rheumatoid arthritis in adults. Also this is a COVID-19 related research chemical.

References : Fridman J. S. et al.: J. Immunol., 184(9), 5298-5307, 2010; Jabbari A. et al. EBioMedicine 2(4), 351-5, 2015; Khan I. M. et al.: Int. J. Obes (Lond) 39(11), 1607-1618, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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