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Basmisanil

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SI-7080

Basmisanil, >98% (HPLC)

CAS No. : [1159600-41-5]

Synonyms : RO-5186582; RG-1662

IUPAC Name : (1,1-Dioxidothiomorpholino)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H20FN3O5S
Mol. Weight :
445.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Basmisanil selectively targets α5‑containing GABAA receptors as a potent negative allosteric modulator (Ki = 5 nM; IC50 = 8 nM). Its pharmacological profile makes it a valuable tool for investigating α5‑mediated inhibitory signaling in cognitive and psychiatric‑disorder models.

References : Joerg F. Hipp. et al.: Sci. Rep., 11(1), 7700, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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