Batoprotafib

SI-6712

Batoprotafib, >98% (HPLC)

CAS No. : [1801765-04-7]

Synonyms : TNO-155

IUPAC Name : (3S,4S)-8-(6-Amino-5-((2-amino-3-chloropyridin-4-yl)thio)pyrazin-2-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Batoprotafib is an orally active allosteric SHP2 inhibitor with strong potency (IC₅₀ = 0.011 µM). It serves as a valuable tool for probing SHP2‑ and RTK‑dependent oncogenic pathways in advanced solid tumor models.

References : TNO155: SHP2 inhibitor, Liu C. et al.: Clin. Cancer Res., 27(1), 342-354, 2021; Weiss A. et al.: Cancer Discov., 12(6), 1500-1517, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.