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BAY-1143269

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SI-6903

BAY-1143269, >98% (HPLC)

CAS No. : [1426928-20-2]

Synonyms : MNK1/2-IN-5

IUPAC Name : (R)-2-((3-(Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6-yl)oxy)propan-1-amine

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Chemical Properites
Mol. Formula :
C17H16N4O2
Mol. Weight :
308.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BAY-1143269 selectively inhibits MNK1 and MNK2 with high potency and is being explored as a therapeutic candidate for diseases driven by dysregulated MNK‑mediated translational control.

References :
Xu W. et al.: J. Med. Chem., 65(2), 983-1007, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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