BAY-1165747

SI-7932

BAY-1165747, >98% (HPLC)

CAS No. : [1609342-18-8]

Synonyms : BAY-747

IUPAC Name : (S)-N-(2-Amino-2-methylbutyl)-8-((2,6-difluorobenzyl)oxy)-2,6-dimethylimidazo[1,2-a]pyridine-3-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BAY 1165747 is a brain‑penetrant oral sGC stimulator that improves cognition in L‑NAME‑induced memory‑deficit models and lowers blood pressure across rat models. It also enhances skeletal‑muscle performance in mdx/mTRG2 mice, indicating therapeutic potential in Duchenne muscular dystrophy and related neuromuscular disorders.

References : Nelissen E. et al.: Sci. Rep., 12(1), 3589, 2022; Vakalopoulos A. et al.: J. Med. Chem., 2023; Krishnan S. M. et al.: Int. J. Mol. Sci., 22(15), 8016, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.