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BAY-1217389

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SI-6629

BAY-1217389, >98% (HPLC)

CAS No. : [1554458-53-5]

IUPAC Name : N-Cyclopropyl-4-(6-(2,3-difluoro-4-methoxyphenoxy)-8-((3,3,3-trifluoropropyl)amino)imidazo[1,2-b]pyridazin-3-yl)-2-methylbenzamide

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Chemical Properites
Mol. Formula :
C27H24F5N5O3
Mol. Weight :
561.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BAY-1217389 potently inhibits the mitotic checkpoint kinase Mps1 with sub‑10‑nM activity, making it a valuable tool for probing spindle‑assembly checkpoint signaling and Mps1‑dependent cancer pathways.

References : Wengner A. M. et al.: Mol. Cancer Ther., 15(4), 583-92, 2016; Wengner A. M. et al.: Mol. Cancer Ther., 15(4), 583-92, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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