BAY-8400

SI-6843

BAY-8400, >98% (HPLC)

CAS No. : [2763602-59-9]

IUPAC Name : 8-(5-(Difluoromethyl)pyridin-3-yl)-1-(2,3,6,7-tetrahydrooxepin-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BAY‑8400 selectively inhibits DNA‑PK with nanomolar potency (IC₅₀ = 81 nM) and is orally bioactive. It serves as a valuable tool for investigating DNA‑PK–dependent DNA‑repair pathways and their therapeutic relevance in cancer models.

References : Berger M. et al.: J. Med. Chem., 10.1021/acs.jmedchem.1c00762, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.