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BAY 87-2243

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SI-6946

BAY 87-2243, >98% (HPLC)

CAS No. : [1227158-85-1]

IUPAC Name : 5-(1-((2-(4-Cyclopropylpiperazin-1-yl)pyridin-4-yl)methyl)-5-methyl-1H-pyrazol-3-yl)-3-(4-(trifluoromethoxy)phenyl)-1,2,4-oxadiazole

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C26H26F3N7O2
Mol. Weight :
525.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BAY 87‑2243 selectively inhibits hypoxia‑inducible factor‑1 (HIF‑1) with high potency, blocking HIF‑1–mediated transcriptional responses to hypoxia and serving as a valuable tool for studying HIF‑regulated tumor biology.

References : Ellinghaus P. et al.: Cancer Med., 2(5), 611-24, 2013; Helbig L. et al.: Radiat. Oncol., 9, 207, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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