BD-7148

SI-8073

BD-7148, >98% (HPLC)

CAS No. : [3037514-35-2]

IUPAC Name : 4-(3-(4-((3-Benzyl-9-methyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepin-2-yl)ethynyl)-1H-pyrazol-1-yl)azetidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BD‑7148 is a highly selective BRD4‑targeting PROTAC degrader developed for preclinical oncology applications. It induces nanomolar BRD4 degradation with strong selectivity over BRD2/BRD3 and suppresses BRD4‑dependent transcriptional programs, resulting in potent antiproliferative activity in BRD4‑driven cancer models.

References : Hu J. et al.: J. Med. Chem., 66(12), 8222-8237, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.