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BEBT-109

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SI-7853

BEBT-109, >98% (HPLC)

CAS No. : [2050906-40-4]

IUPAC Name : N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(5-methoxy-1H-pyrrolo[3,2-b]pyridin-1-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

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Chemical Properites
Mol. Formula :
C27H32N8O3
Mol. Weight :
516.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : BEBT‑109 is a pan‑mutant‑selective EGFR inhibitor with strong potency and improved pharmacokinetic behavior. Its broad activity against multiple oncogenic EGFR mutations makes it a valuable tool for investigating mutant‑EGFR–driven NSCLC biology and therapeutic strategies.

References : Fan F. et al: Transl Oncol., 14(2), 100961, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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