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Bepotastine n-butyl ester (SBPB)

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Bepotastine n-butyl ester (SBPB), >98%

CAS No. : [1807606-59-2]

IUPAC Name : Butyl (S)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoate

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Chemical Properites
Mol. Formula :
C25H33ClN2O3
Mol. Weight :
445
Appearance :
Brown liquid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog or impurity of Bepotastine, which is a selective, orally active second-generation histamine H1 receptor antagonist that can suppress nerve growth factor (NGF) expression. Bepotastine shows potential for research into allergic rhinitis, allergic conjunctivitis, and urticaria or pruritus.

References : Kida T. et al.: Exp Eye Res., 91(1), 85-91, 2010; Kamata Y. et al.: J. Dermatol Sci., S0923-1811(18), 30186-5, 2018; Tanizaki H. et al.: Int Arch Allergy Immunol., 145(4), 277-82, 2008; Jon I Williams et al.: Curr Med Res Opin., 26(10), 2329-38, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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