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Bexarotene

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SI-6574

Bexarotene, >98% (HPLC)

CAS No. : [153559-49-0]

Synonyms : LGD-1069

IUPAC Name : 4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C24H28O2
Mol. Weight :
348.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Bexarotene selectively activates RXRα, RXRβ, and RXRγ with EC50 values of 33–25 nM while showing very limited activity at RAR receptors. Its RXR‑targeted mechanism makes it a valuable tool compound for investigating RXR signaling and cutaneous T‑cell lymphoma biology.

References : Nathalia Rodrigues de Almeida. et al.: Med. Res. Rev., 39(4), 1372-1397, 2019; Danyang Shen. et al.: Onco. Targets Ther., 12, 7877-7886, 2019; Y. Wang. et al.: Oncogene, 25(9), 1320-9, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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