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Bezafibrate 5-O-beta-D-glucuronide

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SI-7991

Bezafibrate 5-O-β-D-glucuronide, >98% (HPLC)

Synonyms : β-D-GlcUA-bezafibrate

IUPAC Name : (2R,3R,4R,5S)-6-((2-(4-(2-(4-Chlorobenzamido)ethyl)phenoxy)-2-methylpropanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C25H28ClNO10
Mol. Weight :
537.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Bezafibrate 5‑O‑β‑D‑glucuronide is the major glucuronidated metabolite of bezafibrate, formed via phase II metabolism. It retains the core fibrate scaffold but is conjugated at the 5‑hydroxy position with β‑D‑glucuronic acid, greatly increasing polarity and facilitating renal excretion. This metabolite is commonly used in studies of bezafibrate biotransformation, pharmacokinetics, and PPAR‑related lipid metabolism.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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