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Bezafibrate-d4

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SI-7986

Bezafibrate-d4, >98% (HPLC)

CAS No. : [1189452-53-6]

Synonyms : BM-15075-d4

IUPAC Name : 2-(4-(2-(4-Chlorobenzamido-2,3,5,6-d4)ethyl)phenoxy)-2-methylpropanoic acid

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Chemical Properites
Mol. Formula :
C19H16D4ClNO4
Mol. Weight :
365.85
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Bezafibrate‑d4 is a deuterium labelled version of Bezafibrate, a pan‑PPAR agonist exhibiting micromolar activity across PPARα, PPARγ, and PPARδ in both human and murine systems. The parent molecule is clinically used as a hypolipidemic drug and serves as a benchmark compound in PPAR signaling studies.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Willson T. M. et al.: J. Med. Chem., 43(4), 527-50, 2000; Usui-Ouchi A. et al.: Int. Immunopharmacol., 52, 70-76, 2017; Franko A. et al.: Mol. Metab., 6(3), 256-26, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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