BI -7446

SI-8163

BI -7446, >98% (HPLC)

CAS No. : [2767011-00-5]

IUPAC Name : 1-((2R,5R,7R,8R,10R,12aR,14R,15R,15aS,16R)-14-(6-Amino-9H-purin-9-yl)-15-fluoro-16-hydroxy-2,10-dimercapto-2,10-dioxidooctahydro-12H-5,8-methanofuro[3,2-l][1,3,6,9,11]pentaoxa[2,10]diphosphacyclotetradecin-7-yl)-1,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : BI-7446 is a cyclic‑dinucleotide STING agonist that robustly activates all five human STING variants, driving type I interferon signaling and tumor‑directed immune responses. It is useful for probing STING‑dependent mechanisms in cancer immunotherapy research.

References : Kuttruff C. A. et al.: J. Med. Chem., 66(14), 9376-9400, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.